LETTER FROM THE EDITOR-IN-CHIEF

Abstract

Dear Faculty, Colleagues, and Readers

Today, Sunday, October 9^th 2022, is an important day in the history of Tan Tao University (TTU) because today, the School of Medicine teams up with the School of Biotechnology to launch the first issue of TTU Journal of Biomedical Sciences.

In this first issue, focusing on cardiovascular diseases, T Nguyen et al. lead the discussion by listing the current Questions on the Genesis and Growth of Coronary Lesions and their Answers Based on Fluid Mechanics Engineering. (1) This is the first time when the flow dynamic of coronary and peripheral arteries was investigated from a fluid mechanics perspective. The study could be performed because the investigator team had redesigned and reprogrammed the current recording and reviewing technique of coronary angiography. As a result, the authors could display detailed images of collision, water hammer shock, recirculating flow, vortex formation, and especially cavitation in coronary arteries. Usually, explanations of these hydraulic phenomena are restricted to the area of expertise of fluid mechanics engineers or physicists. Now, this is the first time that cardiologists have discussed in depth the hydraulic principles and practice considering arteries and veins as pipes and the left ventricle as the pump.

In the next 3 papers, Rigatelli G, Zuin M, and Vu T Loc discussed the principles and applications of Computer Fluid Dynamics (CFD), Artificial Intelligence (AI) and Machine Learning in current cardiovascular research. (2-4) These three articles are crucial for the clinical or practical implications of new ideas or new technologies. (1) Even the new ideas could be provocative or innovative, their clinical bedside applications are important and meaningful for society, patients and researchers. 

In the next paper of T Nguyen et al., the main focus was to question the Presence of Chest Pain and Syncope in patients with Aortic Stenosis and patent coronary arteries. (5) This was a paradoxical presentation because of how a patient with normal coronary arteries could have a cardiac arrest and die. The answer from fluid mechanics perspective may help to prevent sudden death, syncope, or chest pain in patients with aortic stenosis.

In the paper Unmasking Syndrome X, the aim of the study was to explain the cause of recurrent chest pain, which plagued many women of every age group and social background. (6) Paradoxically, these patients had patent coronary arteries. The authors believe an abnormal flow with a prolonged arterial phase was the culprit.

In the last paper on Measuring the Size and Expansion of the Common Femoral Vein as a new method of detection and stratification of heart failure, the goals were to confirm and detect heart failure (HF) at its earliest. (7) In this study, from a fluid mechanics perspective, the body began to accumulate fluid in the large veins even though there was no symptom. As a result, the new technique of measuring the size of the femoral vein, distal to the origin of the profunda was the best way for preemptive treatment of HF.

After the successful inauguration of this first issue, the editorial team will submit the published articles for incorporation in the Digital Access to Scholarship at Harvard (DASH.Harvard.edu), which is the central, open-access repository of research by members of the Harvard University community.

With the successful inauguration of this first issue, I would like to commend the managing team, Dr. Ta Van Quang, Dr. Nguyen Thanh Dien, and Dr. Lam Thien Ngoc, for the great success of this journal.

I would like to invite clinicians or researchers to submit the manuscript to the TTU Journal of Biomedical sciences (TJBS). You could submit your expertise and recent achievements in the following areas: clinical science, dental, nursing, other related medical fields, and biotechnology. The TJBS has a team of your students to help in polishing the English language of the papers.

In the next issue of TJBS, Dr. Peter Singer from the University of Southern California will discuss the latest updates on Endocrinology. Dr. Meden F. Isaac-Lam from Purdue University Northwest will discuss the applications of Synthesis and Photodynamic Activity in medicine. Arvinda Nanjundappa, MD, from Cleveland Clinics, will submit a paper on the performance of peripheral angioplasty and stenting of the iliac arteries. All papers published in the TJBS will be submitted for incorporation in DASH.

At the end, I would like to wish all faculty, colleagues, and readers a great new academic year 2022-2023.

With my warmest personal regards,

Thach Nguyen MD FACC FSCAI

Editor-In-Chief